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Description
As a physician I know her work is backed up by studies and a lot of knowledge in epigenetics but most importantly common sense

Long enough for most structural changes to return to baseline but short enough to maintain protocol feasibility

Raison, C

A four-week hold is roughly the window needed for a step to reach steady state and for the gut to adapt to it, which is why escalating before the block is complete effectively means judging a dose you have not yet fully experienced
