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It also had anti-inflammatory properties as it downregulated the levels of interleukin 1, tumor necrotic factor-, and transforming growth factor-

321 Nuclear cap binding protein subunit 2 (NCBP2) NCBP2 exhibited significant upregulation in pancreatic cancer tissues compared with normal tissues

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171 Making the reasonable assumption that the mechanisms behind the life-prolonging effects of DR are also responsible for its antitumor action, one would have to conclude that DR in humans is most effective if it could replace a diet leading to weight gain and metabolic disturbances when consumed ad libitum