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The mechanism through which external factors contribute to the irregular proliferation of keratinocytes and the progression to psoriatic lesions involves innate and adaptive immunity cells ( The presence of autoantigens which trigger the expansion of autoreactive T cells has prompted researchers to investigate psoriasis as an autoimmune disease

Hyperammonemic encephalopathy in multiple myeloma

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Transfusion-dependent -thalassemia patients may experience brain iron overload, potentially leading to cognitive impairment, in contrast to non-transfusion-dependent patients [43]