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Episodes of gouty arthritis that occur in childhood, in early adults or in pre-menopausal women should suggest an underlying inherited enzyme defect or the ingestion of some agent that interferes with uric acid metabolism
Proteasome Dysfunction Mediates High Glucose-Induced Apoptosis in Rodent Beta Cells and Human Islets
Jalleh RJ, Jones KL, Rayner CK, Marathe CS, Wu T, Horowitz M
