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Overexpression of GLS2 may contribute to drug resistance following treatment of breast cancer cells with the GLS inhibitor CB-839 (94)
Because of the ubiquitous nature and broad availability of the drug, this has resulted in APAP hepatotoxicity being the most frequent cause of acute liver failure (ALF) in the US2 and other Western countries3
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doi: 10.1371/journal.pone.0129327
