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In in silico modelling 38 , an apparently optimal state of triploidy in cancer was achieved more efficiently by initially tetraploid cells than by diploid cells, presumably as a result of the ability of the former to buffer lethal events such as nullisomy
These data were in accord with several evidences demonstrating that ER stress induces apoptosis via CHOP [50], triggers the surface translocation of CRT and the CRT-mediated phagocytosis [3, 6]
Guo Y-S, Zhang F, Yang J, Wang F-F, NuLi Y, Hirano S-I
doi: 10.3390/ijms13022078
