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The alanine substitution of four key interacting residues at the self-association interface suppressed this aggregation, strongly supporting our hypothesis that the self-association interface is involved in the early stages of APOE aggregation

[DOI] [PubMed] [Google Scholar] 21.Incalza M.A., DOria R., Natalicchio A., Perrini S., Laviola L., Giorgino F
