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In other words, the lack of vitamin C biosynthesis allows our bodies to know more about our nutritional status and consequently set the proper baseline of HIF1 expression
Attempting to turn a chemopreventive approach into a pharmaceutical strategy would be foolhardy, but to the extent that sulforaphane is proven to have curative or therapeutic properties, this could be a direction in which to turn
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
Pelaia G, Vatrella A, Gallelli L, Renda T, Caputi M, Maselli R, Marsico SA
