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Studies have shown that NAD switches off the genes of aging, helping to extend life span, increases endurance, improves cognitive function, and enhances cellular energy

In the electron transport chain (ETC), FMN and FAD function as cofactors that shuttle electrons, acting especially in I and II complexes, which contain flavoproteins reductases and electron transferring flavoproteins, thereby facilitating the production of adenosine triphosphate (ATP), the primary energy source of cells, being particularly important in the nervous system, due to its high energy demands (, , )

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Deficiency occurs either when a person is not consuming enough B12-rich foods (such as meat, dairy, and fortified cereals) or when the body is unable to absorb the vitamin effectively due to certain medical conditions or digestive issues