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Description
The major biological factors that drive the observed sex differences in AD include differences in age-related sex hormone reduction, the incidence of genetic risks (ApoE, etc.), the impact from risks of other diseases (diabetes, depression, cardiovascular disease), and the age-related declines in brain volume and brain glucose metabolism (247, 252, 258, 263)
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This point is critical to understanding the neurodegeneration associated with lipid peroxidation
