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Transition to maintenance once desired skin tone is reached

Two other members of the VEGF receptor family are VEGFR-1 and VEGFR-3, which also bind members from the VEGF family (34)

[0366] In another embodiment, a recombinant DNA vector is used to transfect a cell line that produces an antibody having a desired effector function, (e.g., a constant region of a human immunoglobulin) in which case, the replacement gene contained in the recombinant vector may encode all or a portion of a region of an ALPPL2/ALPP specific antibody and the target sequence contained in the recombinant vector allows for homologous recombination and targeted gene modification within the antibody producing cell

This is significant, as cysteine is spontaneously catabolized in the GI tract and bloodstream, and its supplementation alone can produce toxicity [33]