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Vitamin B12 and MTHFR Treatment Feb 7, 2019 1 min read Updated: Feb 21, 2019 Dr

The evidence base for tirzepatide as monotherapy is robust, with pivotal trials including SURMOUNT-1 demonstrating significant weight reduction in adults with obesity, and SURPASS trials establishing glycemic efficacy in type 2 diabetes

Studies suggest that subsequent weight regain, if it does occur, is usually precipitated by an injury or severe environmental stressors which disrupt the maintenance routine

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