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Recent studies suggested that one of the enzymes inhibited by auranofin is GSTP1-1 (Fig

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Of those 20, lutein and zeaxanthin are the only two (macular carotenoids) that are deposited in high quantities into the macular portion of the eyes, which is one of the earliest to be damaged during aging

These observations underline the potency of NFT as a pharmacological Nrf2 activator