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As an example, low doses of resveratrol increase endothelial nitric oxide synthase (eNOS) activity and vascular repair but at high dosages inhibits VEGF signaling and endothelial proliferation, acting as an anti-tumor agent [27, 28, 156]
Natural product Piperlongumine inhibits proliferation of oral squamous carcinoma cells by inducing ferroptosis and inhibiting intracellular antioxidant capacity

In the case of COPD, a 2018 pilot study found that Ramadan Intermittent Fasting (RIF) had no significant impact on spirometric data in male patients with COPD [73]

haemophilum by 16s-rRNA gene sequencing
