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Second, there was significant clinical heterogeneity in the 21 studies with differences in composition, dose, and dosage form of CHM, as well as differences in interventions (type of WM) and duration of intervention in the control group

doi: 10.1016/j.celrep.2019.02.042 132 du BoisHHeimTALundAW
Most certainly, the sinus ligated to the bone ascertained definitive occlusion, skull bone overlying the sinus eliminated the risk of sinus tear

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