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Many people for whom life has been difficult, either due to one stressor or a series of stressors, appear to age very fast and start showing grey hair
doi: 10.1016/0304-3940(94)90345-x, PMID: [DOI] [PubMed] [Google Scholar] 86.Dubbioso R, Spisto M, Hausdorff JM, Aceto G, Iuzzolino VV, Senerchia G, et al
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FBXL5, a substrate recognition component of the SCF E3 ligase complex, recruits IRP2 for ubiquitination and degradation
