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Later, the association between proteosomal inhibition and apoptosis induction by curcumin was investigated on both HCT-116 and SW480 cells treated for 24 h by measuring the activation of caspase-3/-7 activation and PARP cleavage and performing the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay

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While catalase is a valuable factor in cardiovascular protection, translating these findings to clinical applications necessitates a thorough mechanistic understanding and targeted modulations of catalase activity in various cardiovascular conditions [70]

Biomaterials 150 , 137143 (2018)