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Description
Thiopurine drugs have a relatively narrow therapeutic index and are capable of causing lifethreatening toxicity, most often myelosuppression (Sahasranaman et al., 2008)
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10.1186/1471-2180-10-140 BMC Microbiol
The activation and proliferation of glial cells, in turn, are useful in order to release signaling factors and to trigger a robust immune reaction consisting of brain-resident as well as peripherally recruited inflammatory cells
