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Several studies have confirmed that cryotherapy can reduce inflammation

J Clin Endocrinol Metab 80 : 26332637 Mulligan K and Schambelan M (2002) Anabolic treatment with GH, IGF-I, or anabolic steroids in patients with HIV-associated wasting

Vitamin B12 (B12) is an essential cofactor for two enzymes involved in onecarbon metabolism: methylmalonyl CoA mutase (reduced function of this enzyme results in increased serum methylmalonyl acid (MMA) levels) and methionine synthetase (this enzyme catalyzes the remethylmation of homocysteine to methionine)

Acting to fight the signs of aging, glutathione is a potent antioxidant that can help prevent and reverse the effects of free radicals by clearing the body of oxidation and free radicals that lead to hyperpigmentation, age spots, sun spots, wrinkles, acne, and even melasma