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In experimental autoimmune encephalomyelitis (a model of multiple sclerosis), berberine reduces the permeability of the blood-brain barrier and inhibits the activity of matrix metalloprotease 9 (MMP-9) in the cerebrospinal fluid and the brain of model mice (Ma et al., 2010)
62 SchnekenburgerM.MorceauF.DuvoixA.DelhalleS.TrentesauxC.DicatoM.et al (2004)
Could autophagy dysregulation link neurotropic viruses to Alzheimers disease
