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Description
DAMPs released from ferroptotic cellssuch as lipid oxidation products [hydroxynonenal (4-HNE) and oxidized phospholipids (oxPLs)], HMGB1, and dsDNAactivate the TLR4-MyD88-NF-B and cGAS-STING pathways, driving the production of proinflammatory cytokines and type I interferons (Wang et al., 2019

As localized on the cell surface, these molecules drive interactions with the environment and other cells, particularly with host immune cells

P., Borges, T
Fenech M
