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New therapeutic targets will be generated by understanding the mechanistic consequences of up and down-regulating MGF

This treatment can increase T cell infiltration by inhibiting the proliferation and migration of CAFs through negative regulation of the MAPK/ERK pathway, thereby decreasing the secretion of vascular cell adhesion molecule-1 (VCAM-1) (122)

Institutional conflict of interest: attempting to crack the deferiprone mystery

These mice underwent a 3-week regimen of CPZ and GENUS or constant light and sound simultaneously and were subsequently sacrificed (Supplementary Fig