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Neuroinflammation in Alzheimers disease: insights from peripheral immune cells
Accordingly, prominent sex differences exist in oxidative stress, as females are proposed to have overall lower levels of ROS-induced damage, reduced mitochondrial DNA damage, and higher antioxidant enzyme levels, thus being less vulnerable to oxidative insults than males (246, 249, 256)
Furthermore, e x vivo LPS-stimulated cells showed a significantly lower OCR for spare respiratory capacity compared to ConA-stimulated PBMC
