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In addition, the labile iron pool causes the release of hazardous ROS (7) and oxidative stress (46) via Fenton reaction (Fe2+ + H2O2 Fe3+ + OH + OH) (46)
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These free radicals are natural byproducts of cellular metabolism, but when they accumulate, they cause severe oxidative stress, damaging lipids, proteins, and DNA
Peiro, G., Alary, J., Cravedi, J., Rathahao, E., Steghens, J., & Guraud, F
