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Though anecdotal reports are common, large-scale human trials remain limited, highlighting the need for further scientific validation

In other words, the preclinical signal appears against a backdrop of controlled energy intake and activity, not as a standalone effect that overrides diet

To date several clinical trials have been conducted to test IGF-1 under several conditions and an infinity of animal models have been used to investigate its deficiency, treatment and to exploit its actions

The lack of adequate vitamin B12 from sources such as meat, eggs, and dairy, can lead to deficiencies causing anemia, intestinal issues, and other medical conditions