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The NER signaling pathway can repair platinum-induced adducts, therefore, upregulation of NER genes, including ERCC1, ERCC2-XPD, ERCC3-XPB, ERCC4-XPF, ERCC5-XPG, ERCC6, ERCC8 and XPA, might mediate chemoresistance [63]
giving final approval of the version to be published
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This review brings together current knowledge on the plants bioactive constituents, traditional applications, pharmacological properties, pharmacokinetics, toxicity, and prospective pharmaceutical uses
