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Mitigative Effects on Metabolic-Associated Fatty Liver Disease (MAFLD) (Figure 1E) CGA inhibits HMG-CoA reductase, thus reducing the quantity of palmitic acid, oleic acid, or linoleic acid-induced large lipid droplets in the hepatic cell line HepG2 [162,163]

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However, there are many proteins that are indirectly activated by ROS, including transcription factors, such as hypoxia-inducible factor (HIF) and nuclear factor-B (NF-B), and kinases, like Src and AMP-activated protein kinase