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These data underscore oxidative stress as both a contributor to and a consequence of metabolic dysregulation in diabetic renal injury

The mechanism of action overlaps substantially with the physiological changes produced by bariatric surgery itself, particularly Roux-en-Y gastric bypass and sleeve gastrectomy, which both increase endogenous GLP-1 secretion

In this review, we summarized the physiological and pathological mechanisms of the HGF/c-Met in liver regeneration

This is not merely additive: the MOTS-c may amplify or extend the mitochondrial biogenesis signal beyond what training alone achieves, particularly in older adults whose endogenous MOTS-c response to exercise is blunted [2]
