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Moreover the hormonal rearrangement intrinsic of pregnancy [17] redistributes the interrelationships of metabolic pathways that sustain fetus growth and differentiation, particularly in rats, that have a short pregnancy (about 17 d)

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To enhance the feasibility of utilizing intratumoral microbiomes in tumor diagnosis and treatment, it is imperative to precisely detect and identify low-abundance microbial populations within tumors, followed by their cultivation for the analysis and verification of their biological functions, thereby revealing microbiota-host interactions in the tumor microenvironment (Fig