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DM4, N 2 '-Deacetyl-N 2 '-(4-mercapto-4-methyl-1-oxopentyl)-maytansine # Mylotarg was first approved in 2000, withdrawn in 2010, and re-approved in 2017 The growing success of FDA-approved ADCs has fueled major optimism in the field, with around 300 ADC candidates currently in clinical trials
