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The multiple sequence alignment was created using the EMBL Clustal Omega program ( and the resulting alignment was visualized andcolored-coded using the Jalview Desktop application ( Extended Data Fig

Alternatively, multiple lines of evidence suggest that mitochondrial dysfunction may play a role in psychiatric disorders [182], Moreover, there is a high comorbidity rate between mitochondrial diseases and mental disorders [183,184]

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Therapeutic effects of colchicine in the management of Peyronie's disease: a randomized double-blind, placebo-controlled study
