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Mitochondrial-derived peptides are down regulated in diabetes subjects

Furthermore, signal transducer and activator of transcription 3 (STAT3) can inhibit the mTOR/HIF-1 pathway by activating AMP-activated protein kinase (AMPK), leading to reduced cell proliferation and increased apoptosis (38)

[DOI] [PMC free article] [PubMed] [Google Scholar] 162.De La Fuente-Nez C., Korolik V., Bains M., Nguyen U., Breidenstein E.B., Horsman S., Lewenza S., Burrows L., Hancock R.E
