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Description
Several urinary metabolites derived from cytochrome P450 2E1 mediated bioactivation of furan to the highly reactive intermediate cis -2-butene-1,4-dial (BDA) and subsequent reaction of BDA with cellular nucleophiles such as free or protein-bound lysine and cysteine residues and glutathione (GSH) have been suggested as potential biomarkers of furan exposure (Kellert et al

Molecular subtypes and prognostic signature of pyroptosis-related lncRNAs in glioma patients

doi: 10.12659/MSM.882125

In that sense, in silico modeling and molecular dynamics (MD) simulations showed structural changes in the -SNAP M105I mutant protein and the conceals of the hydrophobic amino acids of the N-terminal loop
