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Adult OPC also undergo several forms of peculiar reactivity: some of them transform form into bipolar cells resembling foetal OPC, which migrate towards the lesion

The dysregulation of macrophage activity has been linked to a variety of conditions, such as infectious diseases, autoimmune disorders, cancer, and chronic inflammatory diseases (58)
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According to a study analyzing 71 cases of LM, 24 extrafacial lesions account for 17.5% of all LM/LMM cases, with patients being significantly younger when compared to head and neck LM/LMM patients