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Physical changes such as fat loss or muscle growth typically take longer to become noticeable

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Estimates suggest that the prevalence of DPN among adults with diabetes ranges from 6 to 51% [2, 3]

Psychological stress, exercise, pregnancy, breastfeeding, a high metabolic rate, sickness, inflammatory diseases, diabetes, and excessive urination can deplete thiamine quickly (sometimes in a day), increasing the need for it
