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It appears to: improve blood flow by improving the utilization of fatty acids for energy, which can help reduce muscle fatigue, increase oxygen supply to the affected limbs, and improve walking capacity reduce symptoms, such as leg pain (claudication), and improve the walking distance before the onset of pain

polium was reported in-vivo in rats using carrageenan-induced inflammation and cotton pellet granuloma models at doses ranging from 50 to 150 mg/kg in carrageenan-induced inflammation and at a dose of 500 mg/kg in cotton-pellet granuloma models (Tariq et al., 1989

doi: 10.1088/1758-5090/ac0c5e 195 MalikMYangYFathiPMahlerGJEschMB

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