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Description
Cell 188 , 55555575.e26 (2025)
The mass spectrum in positive ionization mode for complex 2 after 1 min of incubation showed three signals, one at m/z = 613 corresponding to the GSSG and two signals of an iron complex at m/z = 254 and at m/z = 376, corresponding to the [M L] + and [M + Na] + species
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Genetic variants of AGXT (alanine glyoxylate aminotransferase) gene coding for alanine glyoxylate aminotransferase (i.e., an enzyme involved in oxalate metabolism) have been correlated with the severity of CIPN in patients on oxaliplatin therapy [26]
