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Neuroscience Letters 282, 1-4CrossRefGoogle ScholarPubMed 51Mehindate, K., Sahlas, D.J., Frankel, D

Primary and secondary alcohols and aldehydes undergo oxidation relatively easily but tertiary alcohols, ketones and carboxylic acids are resistant since such a reaction involves cleavage of C-C bonds

Notably, in the condition of excess hemin exposure and hypoxia, our findings suggest an important contribution of the TSS pathway and its regulation by DMF for de novo cysteine synthesis and GSH generation in protecting against the oxidative and ferroptotic stresses in SCD erythroblasts

10.1016/j.immuni.2017.03.019 66 MandalP