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Description
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications

In one embodiment, the antibody or antigen binding portion thereof according to the present invention binds an antigen (e.g., ALPP and/or ALPPL2) or a cell expressing the antigen with an affinity (K D ) of 5 nM or better (i.e., or less) (e.g., 40 nM or 30 nM or 20 nM or 10 nM or less), as measured using a surface plasmon resonance assay or a cell binding assay

Oncotarget (2016) 7:61136

I think its important to recognize that we might have a model of who someone is, says Dossett, or a model of how someone should conduct themselves
