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Their growing popularity, especially within the biohacking and bodybuilding communities, comes largely from the fact that they carry significantly fewer side effects and pose less risk of organ damage
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Specifically, SIRT7 is a target of miR-20b, and the inhibition of miR-20b increases the mRNA and protein expression of SIRT7 by direct targeting of the 3-UTR of SIRT7 in HG-treated podocytes, alleviating HG-induced podocyte apoptosis (Qi et al., 2022a)
