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For example, the dimeric copperzinc SOD (SDO1) is present in cytosol, the manganeseSOD (SDO2) is mitochondrial and the tetrameric copperzinc SOD (SOD3) is present in plasma (extracellular environment) [17]
Peptides and therapeutic proteins are the exclusive substances capable of traversing the endothelial tight junctions and reaching the injury site through the intranasal route
Diabetes Metab J 40(5):376385
These inflammatory mediators might stimulate nociceptors, leading to generation and further chronification of painful symptoms
