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For instance, alkaloids like homoharringtonine demonstrate unique advantages in leukemia treatment by inducing cell differentiation

To reach a toxic level, exposure would need to be in the milligram range, significantly more than the trace amounts found in B12 injections or oral b12 tablets

The mean peak level of adducts for subjects in this study was 0.4 nmol/mL (0.2 nmol/mL)
Eur J Clin Invest 33:397401
