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In eye diseases, it prevents the interaction of VEGF with its receptors on the surface of endothelial cells, reducing endothelial cell proliferation, vascular leakage and the formation of new blood vessels in the retina

122,123,124 Mammalian CYPs are a family of heme-containing NAD(P)H-dependent monooxygenases that metabolize numerous endogenous metabolites, including fatty acids and steroids, and exogenous substrates, including carcinogens, pesticides and drugs, resulting in continuous production of ROS

J., Rajan, A., Suriano, F

Hypothalamic AgRP-neurons control peripheral substrate utilization and nutrient partitioning