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The FDA label includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, contraindicating use in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
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First-line obesity treatments include lifestyle intervention (e.g., low-calorie diets) and behavioral modification therapies 4,5 since approved obesity medications have limited efficacy and commonly have side effects 6
