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Brain repair and BBB permeability are strongly linked to lesion volume and stroke severity, as well as to neuroinflammation characterized by activated microglia and inflammatory cytokines[52]

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The symptoms associated with HD are chorea (jerky involuntary movements that affect the hips, shoulders, and face), cognitive decline, dystonia (abnormal muscle tone which results in muscular spasm and posture abnormality), and behavioral difficulties [113]

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