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Additionally, LSCs are also defined by their leukemogenic potential
The liver is the first to be affected (Wang et al
Notably, ER is also localized to the mitochondrial membrane, where it exerts direct non-genomic control over mitochondrial respiration (112,113)
It is characterized by chronic anovulation, hyperandrogenism, insulin resistance, and ovarian morphological changes (Rosenfield and Ehrmann, 2016)
