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Some advice to reduce side effects from physicians well-versed in peptide therapy includes: Start with a lower dose and gradually increase to the prescribed dose
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For example, splicing at SS2 in neurexins modulates binding to dystroglycans, and splicing regulation at SS4 alters the affinity of neurexins for postsynaptic adhesion molecules such as neuroligins, dystroglycans, LRRTMs, calsyntenins, and latrophilins [72, 77, 79]

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