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Microglial cells and astrocytes overexpress the P2X7R receptor which has been shown to be responsible for NLRP3 (cryopyrin, part of the NOD-like receptor family) inflammasome activation and promotes the release of the proinflammatory cytokine interleukin-1 (IL-1)

[DOI] [PMC free article] [PubMed] [Google Scholar] Khadka P
