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At the cellular level, the link between thymosin beta-4 and the regulation of the monomeric actin pool is of particular importance, which can influence the reorganisation of the cytoskeleton under experimental conditions

In case of high-risk patients or new-onset subclinical neurographic changes, starting slowly or lowering the speed and the dose of infusion respectively, might help avoiding the risk of progression of the PN and even improve the PN (Rispoli et al

4 Vitamin B12 is generally considered safe, even at high doses

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