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demonstrated that after HDAC inhibitor (Trichostatin A) treatment, the expression of H3K9Ac and genes of nave CD8 T cells increased, and that HDAC inhibitors may play an important role in regulating gene profile expression and functions of memory CD8+ T cells (100)

It may indicate the increased SELENOP transport across the neural barriers, due to high expression of LRP8 at the BBB, which keeps Se levels relatively stable, even during deficiency periods making an adequate Se pool available in the CNS (Zachara et al., 2001)

doi: 10.1210/er.2008-0027 3 OlarescuNCGunawardaneKHansenTKMollerNJorgensenJOL